PMH49 COST-EFFECTIVENESS OF QUETIAPINE EXTENDED RELEASE VERSUS OTHER ATYPICAL ANTIPSYCHOTICS IN ACUTE BIPOLAR DEPRESSION
نویسندگان
چکیده
منابع مشابه
Effectiveness of the extended release formulation of quetiapine as monotherapy for the treatment of acute bipolar depression.
Background: To evaluate the effectiveness of quetiapine extended release once daily in bipolar depression. Methods: Double-blind, placebo-controlled study in acutely depressed adults with bipolar I or II disorder, with or without rapid cycling.Patients were randomized to 8 weeks of quetiapine extended release(XR) 300 mg daily monotherapy or placebo.The primary out come measure was changed from ...
متن کاملCost effectiveness of quetiapine in patients with acute bipolar depression and in maintenance treatment after an acute depressive episode.
BACKGROUND Bipolar disorder has a significant impact upon a patient's quality of life, imposing a considerable economic burden on the individual, family members and society as a whole. Several medications are indicated for the acute treatment of mania and depression associated with bipolar disorder as well as for maintenance therapy; however, these have varying efficacy, tolerability and costs....
متن کاملThe use of atypical antipsychotics beyond psychoses: efficacy of quetiapine in bipolar disorder
BACKGROUND AND RATIONALE Atypical antpsychotics have been sucessfully used in the treatment of bipolar disorder (BD), either as adjunctive or as monotherapy. Quetiapine is an atypical antipsychotic extensively used in the treatment of psychotic disorders. It has serotonergic and dopaminergic activity and it appears to be selective for the mesolimbic and mesocortical dopamine system. The aim of ...
متن کاملClinical and Cost Consequences of Metabolic Effects of Lurasidone Versus Other Atypical Antipsychotics in Schizophrenia
Objective: To estimate the economic burden of hyperglycemia and diabetes associated with lurasidone versus other atypical antipsychotics in schizophrenia. Methods: A discrete event simulation model was developed to conduct the analysis from both US payer and societal perspectives over a 3-year timeframe. The model, based on the values of metabolic parameters at 1 year of treatment, identified p...
متن کاملQuetiapine monotherapy for bipolar depression
Bipolar depression is more common, disabling, and difficult-to-treat than the manic and hypomanic phases that define bipolar disorder. Unlike the treatment of so-called "unipolar" depressions, antidepressants generally are not indicated as monotherapies for bipolar depressions and recent studies suggest that -even when used in combination with traditional mood stabilizers - antidepressants may ...
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ژورنال
عنوان ژورنال: Value in Health
سال: 2009
ISSN: 1098-3015
DOI: 10.1016/s1098-3015(10)74768-9